Application of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease

Neutrophil elastase is a serine protease that has been implicated in the pathogenesis of inflammatory bowel disease. Due to post-translational control of its activation and high expression of its inhibitors in the gut, measurements of total expression poorly reflect the pool of active, functional ne...

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Detalles Bibliográficos
Autores principales: Anderson, Bethany M., Poole, Daniel P., Aurelio, Luigi, Ng, Garrett Z., Fleischmann, Markus, Kasperkiewicz, Paulina, Morissette, Celine, Drag, Marcin, van Driel, Ian R., Schmidt, Brian L., Vanner, Stephen J., Bunnett, Nigel W., Edgington-Mitchell, Laura E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746801/
https://www.ncbi.nlm.nih.gov/pubmed/31527638
http://dx.doi.org/10.1038/s41598-019-49840-4

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