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Imaging of hepatic drug transporters with [(131)I]6-β-iodomethyl-19-norcholesterol

We examined whether [(131)I]6-β-iodomethyl-19-norcholesterol (NP-59), a cholesterol analog, can be used to measure function of hepatic drug transporters. Hepatic uptake of NP-59 with and without rifampicin was evaluated using HEK293 cells expressing solute carrier transporters. The stability of NP-5...

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Detalles Bibliográficos
Autores principales:	Kobayashi, Masato, Nishi, Kodai, Mizutani, Asuka, Hokama, Tsuzumi, Matsue, Miki, Tsujikawa, Tetsuya, Nakanishi, Takeo, Nishii, Ryuichi, Tamai, Ikumi, Kawai, Keiichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746803/ https://www.ncbi.nlm.nih.gov/pubmed/31527775 http://dx.doi.org/10.1038/s41598-019-50049-8

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