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Levosimendan pretreatment improves survival of septic rats after partial hepatectomy and suppresses iNOS induction in cytokine-stimulated hepatocytes
We evaluated the survival effects and biochemical profiles of levosimendan in septic rats after partial hepatectomy and investigated its effects in cultured hepatocytes. Thirty-two rats underwent 70% hepatectomy and were randomised equally into four groups, followed by lipopolysaccharide (LPS) injec...
Autores principales: | Sakaguchi, Tatsuma, Hashimoto, Yuki, Matsushima, Hideyuki, Hishikawa, Hidehiko, Nishizawa, Mikio, Okumura, Tadayoshi, Kaibori, Masaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746814/ https://www.ncbi.nlm.nih.gov/pubmed/31527618 http://dx.doi.org/10.1038/s41598-019-48792-z |
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