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Discrimination of Prion Strain Targeting in the Central Nervous System via Reactive Astrocyte Heterogeneity in CD44 Expression

Prion diseases or transmissible spongiform encephalopathies are fatal, progressive, neurodegenerative, protein-misfolding disorders. Prion diseases may arise spontaneously, be inherited genetically or be acquired by infection and affect a variety of mammalian species including humans. Prion infectio...

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Detalles Bibliográficos
Autores principales: Bradford, Barry M., Wijaya, Christianus A. W., Mabbott, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746926/
https://www.ncbi.nlm.nih.gov/pubmed/31551718
http://dx.doi.org/10.3389/fncel.2019.00411

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