Emerging Roles of Lipophagy in Health and Disease

The term lipophagy is used to describe the autophagic degradation of lipid droplets, the main lipid storage organelles of eukaryotic cells. Ever since its discovery in 2009, lipophagy has emerged as a significant component of lipid metabolism with important implications for organismal health. This r...

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Autores principales: Kounakis, Konstantinos, Chaniotakis, Manos, Markaki, Maria, Tavernarakis, Nektarios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746960/
https://www.ncbi.nlm.nih.gov/pubmed/31552248
http://dx.doi.org/10.3389/fcell.2019.00185
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author Kounakis, Konstantinos
Chaniotakis, Manos
Markaki, Maria
Tavernarakis, Nektarios
author_facet Kounakis, Konstantinos
Chaniotakis, Manos
Markaki, Maria
Tavernarakis, Nektarios
author_sort Kounakis, Konstantinos
collection PubMed
description The term lipophagy is used to describe the autophagic degradation of lipid droplets, the main lipid storage organelles of eukaryotic cells. Ever since its discovery in 2009, lipophagy has emerged as a significant component of lipid metabolism with important implications for organismal health. This review aims to provide a brief summary of our current knowledge on the mechanisms that are responsible for regulating lipophagy and the impact the process has under physiological and pathological conditions.
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spelling pubmed-67469602019-09-24 Emerging Roles of Lipophagy in Health and Disease Kounakis, Konstantinos Chaniotakis, Manos Markaki, Maria Tavernarakis, Nektarios Front Cell Dev Biol Cell and Developmental Biology The term lipophagy is used to describe the autophagic degradation of lipid droplets, the main lipid storage organelles of eukaryotic cells. Ever since its discovery in 2009, lipophagy has emerged as a significant component of lipid metabolism with important implications for organismal health. This review aims to provide a brief summary of our current knowledge on the mechanisms that are responsible for regulating lipophagy and the impact the process has under physiological and pathological conditions. Frontiers Media S.A. 2019-09-10 /pmc/articles/PMC6746960/ /pubmed/31552248 http://dx.doi.org/10.3389/fcell.2019.00185 Text en Copyright © 2019 Kounakis, Chaniotakis, Markaki and Tavernarakis. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cell and Developmental Biology
Kounakis, Konstantinos
Chaniotakis, Manos
Markaki, Maria
Tavernarakis, Nektarios
Emerging Roles of Lipophagy in Health and Disease
title Emerging Roles of Lipophagy in Health and Disease
title_full Emerging Roles of Lipophagy in Health and Disease
title_fullStr Emerging Roles of Lipophagy in Health and Disease
title_full_unstemmed Emerging Roles of Lipophagy in Health and Disease
title_short Emerging Roles of Lipophagy in Health and Disease
title_sort emerging roles of lipophagy in health and disease
topic Cell and Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746960/
https://www.ncbi.nlm.nih.gov/pubmed/31552248
http://dx.doi.org/10.3389/fcell.2019.00185
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