Cargando…

Hypoxia induces rapid, STAT3 and ROS dependent, mitochondrial translocation of RelA(p65) and IκBα

The nuclear factor-κB (NF-κB) family of transcription factors can directly or indirectly regulate many important areas of biology, including immunity, inflammation and cell survival. One intriguing aspect of NF-κB crosstalk with other cell signalling pathways is its regulation of mitochondrial biolo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ivanova, Iglika G., Perkins, Neil D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746997/ https://www.ncbi.nlm.nih.gov/pubmed/31484794 http://dx.doi.org/10.1042/BSR20192101

Ejemplares similares

Thr(435) phosphorylation regulates RelA (p65) NF-κB subunit transactivation
por: O'Shea, John M., et al.
Publicado: (2010)

The role of RelA (p65) threonine 505 phosphorylation in the regulation of cell growth, survival, and migration
por: Msaki, Aichi, et al.
Publicado: (2011)

Celecoxib Suppresses NF-κB p65 (RelA) and TNFα Expression Signaling in Glioblastoma
por: Ahsan, Hina, et al.
Publicado: (2023)

NF-κB/Rel Transcription Factors in Pancreatic Cancer: Focusing on RelA, c-Rel, and RelB
por: Kabacaoglu, Derya, et al.
Publicado: (2019)

Temporal modulation of the NF-κB RelA network in response to different types of DNA damage
por: Campbell, Amy E., et al.
Publicado: (2021)

Degradation of Promoter-bound p65/RelA Is Essential for the Prompt Termination of the Nuclear Factor κB Response
por: Saccani, Simona, et al.
Publicado: (2004)

Enterovirus 71 2C Protein Inhibits NF-κB Activation by Binding to RelA(p65)
por: Du, Haiwei, et al.
Publicado: (2015)

Subinhibitory Concentrations of Bacteriostatic Antibiotics Induce relA-Dependent and relA-Independent Tolerance to β-Lactams
por: Kudrin, Pavel, et al.
Publicado: (2017)

The NF-κB Subunit RelA/p65 Is Dispensable for Successful Liver Regeneration after Partial Hepatectomy in Mice
por: Ringelhan, Marc, et al.
Publicado: (2012)

LRRC25 Functions as an Inhibitor of NF-κB Signaling Pathway by Promoting p65/RelA for Autophagic Degradation
por: Feng, Yanchun, et al.
Publicado: (2017)

ZBTB2 increases PDK4 expression by transcriptional repression of RelA/p65
por: Kim, Min-Young, et al.
Publicado: (2015)

NF-κB Repression by PIAS3 Mediated RelA SUMOylation
por: Liu, Yuangang, et al.
Publicado: (2012)

Cyclophilin A (CypA) Interacts with NF-κB Subunit, p65/RelA, and Contributes to NF-κB Activation Signaling
por: Sun, Shan, et al.
Publicado: (2014)

NleC, a Type III Secretion Protease, Compromises NF-κB Activation by Targeting p65/RelA
por: Yen, Hilo, et al.
Publicado: (2010)

Influence of the relA gene on ribosome frameshifting
por: Masucci, J., et al.
Publicado: (2002)

Identification of genes responsible for RelA-dependent proliferation arrest in human mammary epithelial cells conditionally expressing RelA
por: Kochupurakkal, Bose S., et al.
Publicado: (2015)

Disabling the Nuclear Translocalization of RelA/NF-κB by a Small Molecule Inhibits Triple-Negative Breast Cancer Growth
por: Kanzaki, Hirotaka, et al.
Publicado: (2021)

RelA/p65 inhibition prevents tendon adhesion by modulating inflammation, cell proliferation, and apoptosis
por: Chen, Shuai, et al.
Publicado: (2017)

A RelA(p65) Thr505 phospho-site mutation reveals an important mechanism regulating NF-κB-dependent liver regeneration and cancer
por: Moles, A, et al.
Publicado: (2016)

8-Oxoguanine DNA glycosylase 1 selectively modulates ROS-responsive NF-κB targets through recruitment of MSK1 and phosphorylation of RelA/p65 at Ser276
por: Xue, Yaoyao, et al.
Publicado: (2023)

Regulation of NF-κB activity by competition between RelA acetylation and ubiquitination
por: Li, Haiying, et al.
Publicado: (2011)

The Serine Phosphatase SerB of Porphyromonas gingivalis Suppresses IL-8 Production by Dephosphorylation of NF-κB RelA/p65
por: Takeuchi, Hiroki, et al.
Publicado: (2013)

Hyperinvasive Meningococci Induce Intra-nuclear Cleavage of the NF-κB Protein p65/RelA by Meningococcal IgA Protease
por: Besbes, Anissa, et al.
Publicado: (2015)

p65/RelA NF‐κB fragments generated by RIPK3 activity regulate tumorigenicity, cell metabolism, and stemness characteristics
por: Touil, Yasmine, et al.
Publicado: (2021)

p300-mediated acetylation of COMMD1 regulates its stability, and the ubiquitylation and nucleolar translocation of the RelA NF-κB subunit
por: O'Hara, Andrew, et al.
Publicado: (2014)

relA Enhances the Adherence of Enteropathogenic Escherichia coli
por: Spira, Beny, et al.
Publicado: (2014)

relA Inactivation Converts Sulfonamides Into Bactericidal Compounds
por: Si, Lizhen, et al.
Publicado: (2021)

Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65
por: Buerki, Christine, et al.
Publicado: (2008)

Transcriptional repression of NFKBIA triggers constitutive IKK‐ and proteasome‐independent p65/RelA activation in senescence
por: Kolesnichenko, Marina, et al.
Publicado: (2021)

Phosphorylation of p65(RelA) on Ser(547) by ATM Represses NF-κB-Dependent Transcription of Specific Genes after Genotoxic Stress
por: Sabatel, Hélène, et al.
Publicado: (2012)

Giardia lamblia Decreases NF-κB p65(RelA) Protein Levels and Modulates LPS-Induced Pro-Inflammatory Response in Macrophages
por: Faria, Clarissa Perez, et al.
Publicado: (2020)

Requirement for the NF-κB Family Member RelA in the Development of Secondary Lymphoid Organs
por: Alcamo, Elizabeth, et al.
Publicado: (2002)

PTPIP51—A New RelA-tionship with the NFκB Signaling Pathway
por: Brobeil, Alexander, et al.
Publicado: (2015)

The NF-κB RelA Transcription Factor Is Critical for Regulatory T Cell Activation and Stability
por: Ronin, Emilie, et al.
Publicado: (2019)

NFκB (RelA) mediates transactivation of hnRNPD in oral cancer cells
por: Kumar, Vikas, et al.
Publicado: (2022)

IκBβ enhances the generation of the low-affinity NFκB/RelA homodimer
por: Tsui, Rachel, et al.
Publicado: (2015)

Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance
por: Hunter, Jill E., et al.
Publicado: (2022)

Extracellular ATP Activates Transcription Factor NF-κB through the P2Z Purinoreceptor by Selectively Targeting NF-κB p65 (RelA)
por: Ferrari, Davide, et al.
Publicado: (1997)

BEX2 has a functional interplay with c-Jun/JNK and p65/RelA in breast cancer
por: Naderi, Ali, et al.
Publicado: (2010)

Suppression of STAT3 Phosphorylation and RelA/p65 Acetylation Mediated by MicroRNA134 Plays a Pivotal Role in the Apoptotic Effect of Lambertianic Acid
por: Sim, Deok Yong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_40svte05v5v2j4et4lhv21vhtg