Interleukin-10 Promotes Porcine Circovirus Type 2 Persistent Infection in Mice and Aggravates the Tissue Lesions by Suppression of T Cell Infiltration

Interleukin (IL)-10, as a key anti-inflammatory cytokine, increases during porcine circovirus type 2 (PCV2) infection, but the role of IL-10 in the process remains to be defined. In the present study, using an IL-10 deficient mice model, we found that IL-10 deficiency prevented the reduction of sple...

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Detalles Bibliográficos
Autores principales: Du, Qian, Zhang, Huan, He, Mingrui, Zhao, Xuan, He, Jia, Cui, Beibei, Yang, Xuefeng, Tong, Dewen, Huang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747007/
https://www.ncbi.nlm.nih.gov/pubmed/31551984
http://dx.doi.org/10.3389/fmicb.2019.02050

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