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Mucosal-Pull Induction of Lung-Resident Memory CD8 T Cells in Parenteral TB Vaccine-Primed Hosts Requires Cognate Antigens and CD4 T Cells
Tissue-resident memory T cells (T(RM)) are critical to host defense at mucosal tissue sites. However, the parenteral route of immunization as the most commonly used immunization route in practice is not effective in inducing mucosal T(RM) cells particularly in the lung. While various respiratory muc...
Autores principales: | Haddadi, Siamak, Vaseghi-Shanjani, Maryam, Yao, Yushi, Afkhami, Sam, D'Agostino, Michael R., Zganiacz, Anna, Jeyanathan, Mangalakumari, Xing, Zhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747041/ https://www.ncbi.nlm.nih.gov/pubmed/31552032 http://dx.doi.org/10.3389/fimmu.2019.02075 |
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