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The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees

Advances in instrumentation and computational analysis in proteomics have opened new doors for honeybee biological research at the molecular and biochemical levels. Proteomics has greatly expanded the understanding of honeybee biology since its introduction in 2005, through which key signaling pathw...

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Detalles Bibliográficos
Autores principales: Altaye, Solomon Zewdu, Meng, Lifeng, Lu, Yao, Li, Jianke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747239/
https://www.ncbi.nlm.nih.gov/pubmed/31480282
http://dx.doi.org/10.3390/ijms20174252
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author Altaye, Solomon Zewdu
Meng, Lifeng
Lu, Yao
Li, Jianke
author_facet Altaye, Solomon Zewdu
Meng, Lifeng
Lu, Yao
Li, Jianke
author_sort Altaye, Solomon Zewdu
collection PubMed
description Advances in instrumentation and computational analysis in proteomics have opened new doors for honeybee biological research at the molecular and biochemical levels. Proteomics has greatly expanded the understanding of honeybee biology since its introduction in 2005, through which key signaling pathways and proteins that drive honeybee development and behavioral physiology have been identified. This is critical for downstream mechanistic investigation by knocking a gene down/out or overexpressing it and being able to attribute a specific phenotype/biochemical change to that gene. Here, we review how emerging proteome research has contributed to the new understanding of honeybee biology. A systematic and comprehensive analysis of global scientific progress in honeybee proteome research is essential for a better understanding of research topics and trends, and is potentially useful for future research directions.
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spelling pubmed-67472392019-09-27 The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees Altaye, Solomon Zewdu Meng, Lifeng Lu, Yao Li, Jianke Int J Mol Sci Review Advances in instrumentation and computational analysis in proteomics have opened new doors for honeybee biological research at the molecular and biochemical levels. Proteomics has greatly expanded the understanding of honeybee biology since its introduction in 2005, through which key signaling pathways and proteins that drive honeybee development and behavioral physiology have been identified. This is critical for downstream mechanistic investigation by knocking a gene down/out or overexpressing it and being able to attribute a specific phenotype/biochemical change to that gene. Here, we review how emerging proteome research has contributed to the new understanding of honeybee biology. A systematic and comprehensive analysis of global scientific progress in honeybee proteome research is essential for a better understanding of research topics and trends, and is potentially useful for future research directions. MDPI 2019-08-30 /pmc/articles/PMC6747239/ /pubmed/31480282 http://dx.doi.org/10.3390/ijms20174252 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Altaye, Solomon Zewdu
Meng, Lifeng
Lu, Yao
Li, Jianke
The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees
title The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees
title_full The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees
title_fullStr The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees
title_full_unstemmed The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees
title_short The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees
title_sort emerging proteomic research facilitates in-depth understanding of the biology of honeybees
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747239/
https://www.ncbi.nlm.nih.gov/pubmed/31480282
http://dx.doi.org/10.3390/ijms20174252
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