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The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees
Advances in instrumentation and computational analysis in proteomics have opened new doors for honeybee biological research at the molecular and biochemical levels. Proteomics has greatly expanded the understanding of honeybee biology since its introduction in 2005, through which key signaling pathw...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747239/ https://www.ncbi.nlm.nih.gov/pubmed/31480282 http://dx.doi.org/10.3390/ijms20174252 |
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author | Altaye, Solomon Zewdu Meng, Lifeng Lu, Yao Li, Jianke |
author_facet | Altaye, Solomon Zewdu Meng, Lifeng Lu, Yao Li, Jianke |
author_sort | Altaye, Solomon Zewdu |
collection | PubMed |
description | Advances in instrumentation and computational analysis in proteomics have opened new doors for honeybee biological research at the molecular and biochemical levels. Proteomics has greatly expanded the understanding of honeybee biology since its introduction in 2005, through which key signaling pathways and proteins that drive honeybee development and behavioral physiology have been identified. This is critical for downstream mechanistic investigation by knocking a gene down/out or overexpressing it and being able to attribute a specific phenotype/biochemical change to that gene. Here, we review how emerging proteome research has contributed to the new understanding of honeybee biology. A systematic and comprehensive analysis of global scientific progress in honeybee proteome research is essential for a better understanding of research topics and trends, and is potentially useful for future research directions. |
format | Online Article Text |
id | pubmed-6747239 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-67472392019-09-27 The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees Altaye, Solomon Zewdu Meng, Lifeng Lu, Yao Li, Jianke Int J Mol Sci Review Advances in instrumentation and computational analysis in proteomics have opened new doors for honeybee biological research at the molecular and biochemical levels. Proteomics has greatly expanded the understanding of honeybee biology since its introduction in 2005, through which key signaling pathways and proteins that drive honeybee development and behavioral physiology have been identified. This is critical for downstream mechanistic investigation by knocking a gene down/out or overexpressing it and being able to attribute a specific phenotype/biochemical change to that gene. Here, we review how emerging proteome research has contributed to the new understanding of honeybee biology. A systematic and comprehensive analysis of global scientific progress in honeybee proteome research is essential for a better understanding of research topics and trends, and is potentially useful for future research directions. MDPI 2019-08-30 /pmc/articles/PMC6747239/ /pubmed/31480282 http://dx.doi.org/10.3390/ijms20174252 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Altaye, Solomon Zewdu Meng, Lifeng Lu, Yao Li, Jianke The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees |
title | The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees |
title_full | The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees |
title_fullStr | The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees |
title_full_unstemmed | The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees |
title_short | The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees |
title_sort | emerging proteomic research facilitates in-depth understanding of the biology of honeybees |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747239/ https://www.ncbi.nlm.nih.gov/pubmed/31480282 http://dx.doi.org/10.3390/ijms20174252 |
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