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Intermedin in Paraventricular Nucleus Attenuates Ang II-Induced Sympathoexcitation through the Inhibition of NADPH Oxidase-Dependent ROS Generation in Obese Rats with Hypertension
Increased reactive oxygen species (ROS) induced by angiotensin II (Ang II) in the paraventricular nucleus (PVN) play a critical role in sympathetic overdrive in hypertension (OH). Intermedin (IMD), a bioactive peptide, has extensive clinically prospects in preventing and treating cardiovascular dise...
Autores principales: | Kang, Ying, Ding, Lei, Dai, Hangbing, Wang, Fangzheng, Zhou, Hong, Gao, Qing, Xiong, Xiaoqing, Zhang, Feng, Song, Tianrun, Yuan, Yan, Zhu, Guoqing, Zhou, Yebo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747263/ https://www.ncbi.nlm.nih.gov/pubmed/31466304 http://dx.doi.org/10.3390/ijms20174217 |
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