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Molecular Subtyping and Prognostic Assessment Based on Tumor Mutation Burden in Patients with Lung Adenocarcinomas

The distinct molecular subtypes of lung cancer are defined by monogenic biomarkers, such as EGFR, KRAS, and ALK rearrangement. Tumor mutation burden (TMB) is a potential biomarker for response to immunotherapy, which is one of the measures for genomic instability. The molecular subtyping based on TM...

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Detalles Bibliográficos
Autores principales:	Wang, Changzheng, Liang, Han, Lin, Cong, Li, Fuqiang, Xie, Guoyun, Qiao, Sitan, Shi, Xulian, Deng, Jianlian, Zhao, Xin, Wu, Kui, Zhang, Xiuqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747282/ https://www.ncbi.nlm.nih.gov/pubmed/31480292 http://dx.doi.org/10.3390/ijms20174251

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