Conformation and Domain Movement Analysis of Human Matrix Metalloproteinase-2: Role of Associated Zn(2+) and Ca(2+) Ions

Matrix metaloproteinase-2 (MMP-2) is an extracellular Zn(2+) protease specific to type I and IV collagens. Its expression is associated with several inflammatory, degenerative, and malignant diseases. Conformational properties, domain movements, and interactions between MMP-2 and its associated meta...

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Detalles Bibliográficos
Autores principales: Voit-Ostricki, Leah, Lovas, Sándor, Watts, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747341/
https://www.ncbi.nlm.nih.gov/pubmed/31461891
http://dx.doi.org/10.3390/ijms20174194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747341/
https://www.ncbi.nlm.nih.gov/pubmed/31461891
http://dx.doi.org/10.3390/ijms20174194

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