CRB2 Loss in Rod Photoreceptors Is Associated with Progressive Loss of Retinal Contrast Sensitivity

Variations in the Crumbs homolog-1 (CRB1) gene are associated with a wide variety of autosomal recessive retinal dystrophies, including early onset retinitis pigmentosa (RP) and Leber congenital amaurosis (LCA). CRB1 belongs to the Crumbs family, which in mammals includes CRB2 and CRB3. Here, we stu...

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Detalles Bibliográficos
Autores principales: Alves, C. Henrique, Boon, Nanda, Mulder, Aat A., Koster, Abraham J., Jost, Carolina R., Wijnholds, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747345/
https://www.ncbi.nlm.nih.gov/pubmed/31438467
http://dx.doi.org/10.3390/ijms20174069

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