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Effects of Grape Seed Extract and Proanthocyanidin B2 on In Vitro Proliferation, Viability, Steroidogenesis, Oxidative Stress, and Cell Signaling in Human Granulosa Cells

Reactive oxygen species (ROS) which lead to oxidative stress affect ovarian function. Grape seed extract (GSE) could be proposed as an effective antioxidant, particularly due to its proanthocyanidin content. In this study, we investigated a dose effect (0, 0.01, 0.1, 1, 10, 50, and 100 μg/mL) of GSE...

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Detalles Bibliográficos
Autores principales: Barbe, Alix, Ramé, Christelle, Mellouk, Namya, Estienne, Anthony, Bongrani, Alice, Brossaud, Adeline, Riva, Antonella, Guérif, Fabrice, Froment, Pascal, Dupont, Joëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747392/
https://www.ncbi.nlm.nih.gov/pubmed/31466336
http://dx.doi.org/10.3390/ijms20174215