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C(2)-Ceramide-Induced Rb-Dominant Senescence-Like Phenotype Leads to Human Breast Cancer MCF-7 Escape from p53-Dependent Cell Death

Ceramide is a sphingolipid which regulates a variety of signaling pathways in eukaryotic cells. Exogenous ceramide has been shown to induce cellular apoptosis. In this study, we observed that exogenous ceramide induced two distinct morphologies of cell fate following C(2)-ceramide treatment between...

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Detalles Bibliográficos
Autores principales:	Chang, Wen-Tsan, Wu, Chang-Yi, Lin, Yin-Chieh, Wu, Min-Tsui, Su, Kai-Li, Yuan, Shyng-Shiou, Wang, Hui-Min David, Fong, Yao, Lin, Yi-Hsiung, Chiu, Chien-Chih
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747432/ https://www.ncbi.nlm.nih.gov/pubmed/31480728 http://dx.doi.org/10.3390/ijms20174292

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