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Different Dynamics in 6aJL2 Proteins Associated with AL Amyloidosis, a Conformational Disease

Light-chain amyloidosis (AL) is the most common systemic amyloidosis and is caused by the deposition of mainly insoluble immunoglobulin light chain amyloid fibrils in multiple organs, causing organ failure and eventually death. The germ-line λ6a has been implicated in AL, where a single point mutant...

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Detalles Bibliográficos
Autores principales: Maya-Martinez, Roberto, French-Pacheco, Leidys, Valdés-García, Gilberto, Pastor, Nina, Amero, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747610/
https://www.ncbi.nlm.nih.gov/pubmed/31438515
http://dx.doi.org/10.3390/ijms20174078