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Cutaneous sarcoidosis in a melanoma scar: A case report

Sarcoidosis is an inflammatory multisystemic disease of unknown etiology with multiple presentations of cutaneous lesions. It characteristically infiltrates scars due to several kind of trauma such as surgery, tattoo and even herpes zoster. We present a case of a 65-year-old woman with progressive d...

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Autores principales: Fournier, Cynthia, Vallée, Sheila, Perron, Émilie, Thérien, Geneviève
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747842/
https://www.ncbi.nlm.nih.gov/pubmed/31555445
http://dx.doi.org/10.1177/2050313X19877274
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author Fournier, Cynthia
Vallée, Sheila
Perron, Émilie
Thérien, Geneviève
author_facet Fournier, Cynthia
Vallée, Sheila
Perron, Émilie
Thérien, Geneviève
author_sort Fournier, Cynthia
collection PubMed
description Sarcoidosis is an inflammatory multisystemic disease of unknown etiology with multiple presentations of cutaneous lesions. It characteristically infiltrates scars due to several kind of trauma such as surgery, tattoo and even herpes zoster. We present a case of a 65-year-old woman with progressive distal paresthesia and motor weakness. She was referred to our dermatology clinic for a new violaceous nodular plaque within an old melanoma scar on the posterior neck. On positron emission tomography–computed tomography, there were multiple enlarged thoracic lymphadenopathy and a fluorodeoxyglucose-avid cutaneous lesion on the posterior neck, right in the melanoma scar. Cutaneous and nerve biopsies showed non-necrotising granulomas, supporting the diagnosis of systemic sarcoidosis and excluding melanoma recurrence with metastasis. It is the first case of cutaneous sarcoidosis arising within a melanoma scar. Interestingly, patients with melanoma have a higher risk of sarcoidosis.
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spelling pubmed-67478422019-09-25 Cutaneous sarcoidosis in a melanoma scar: A case report Fournier, Cynthia Vallée, Sheila Perron, Émilie Thérien, Geneviève SAGE Open Med Case Rep JCMS Case Report Sarcoidosis is an inflammatory multisystemic disease of unknown etiology with multiple presentations of cutaneous lesions. It characteristically infiltrates scars due to several kind of trauma such as surgery, tattoo and even herpes zoster. We present a case of a 65-year-old woman with progressive distal paresthesia and motor weakness. She was referred to our dermatology clinic for a new violaceous nodular plaque within an old melanoma scar on the posterior neck. On positron emission tomography–computed tomography, there were multiple enlarged thoracic lymphadenopathy and a fluorodeoxyglucose-avid cutaneous lesion on the posterior neck, right in the melanoma scar. Cutaneous and nerve biopsies showed non-necrotising granulomas, supporting the diagnosis of systemic sarcoidosis and excluding melanoma recurrence with metastasis. It is the first case of cutaneous sarcoidosis arising within a melanoma scar. Interestingly, patients with melanoma have a higher risk of sarcoidosis. SAGE Publications 2019-09-16 /pmc/articles/PMC6747842/ /pubmed/31555445 http://dx.doi.org/10.1177/2050313X19877274 Text en © The Author(s) 2019 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle JCMS Case Report
Fournier, Cynthia
Vallée, Sheila
Perron, Émilie
Thérien, Geneviève
Cutaneous sarcoidosis in a melanoma scar: A case report
title Cutaneous sarcoidosis in a melanoma scar: A case report
title_full Cutaneous sarcoidosis in a melanoma scar: A case report
title_fullStr Cutaneous sarcoidosis in a melanoma scar: A case report
title_full_unstemmed Cutaneous sarcoidosis in a melanoma scar: A case report
title_short Cutaneous sarcoidosis in a melanoma scar: A case report
title_sort cutaneous sarcoidosis in a melanoma scar: a case report
topic JCMS Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747842/
https://www.ncbi.nlm.nih.gov/pubmed/31555445
http://dx.doi.org/10.1177/2050313X19877274
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