Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER–mitochondria communication during the early phase of ER stress

Close contacts between endoplasmic reticulum and mitochondria enable reciprocal Ca(2+) exchange, a key mechanism in the regulation of mitochondrial bioenergetics. During the early phase of endoplasmic reticulum stress, this inter-organellar communication increases as an adaptive mechanism to ensure...

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Detalles Bibliográficos
Autores principales: Bravo-Sagua, Roberto, Parra, Valentina, Ortiz-Sandoval, Carolina, Navarro-Marquez, Mario, Rodríguez, Andrea E., Diaz-Valdivia, Natalia, Sanhueza, Carlos, Lopez-Crisosto, Camila, Tahbaz, Nasser, Rothermel, Beverly A., Hill, Joseph A., Cifuentes, Mariana, Simmen, Thomas, Quest, Andrew F. G., Lavandero, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748148/
https://www.ncbi.nlm.nih.gov/pubmed/30209302
http://dx.doi.org/10.1038/s41418-018-0197-1

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