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TC2N, a novel oncogene, accelerates tumor progression by suppressing p53 signaling pathway in lung cancer

The protein containing the C2 domain has been well documented for its essential roles in endocytosis, cellular metabolism and cancer. Tac2-N (TC2N) is a tandem C2 domain-containing protein, but its function, including its role in tumorigenesis, remains unknown. Here, we first identified TC2N as a no...

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Detalles Bibliográficos
Autores principales: Hao, Xiang-lin, Han, Fei, Zhang, Ning, Chen, Hong-qiang, Jiang, Xiao, Yin, Li, Liu, Wen-bin, Wang, Dan-dan, Chen, Jian-ping, Cui, Zhi-hong, Ao, Lin, Cao, Jia, Liu, Jin-yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748156/
https://www.ncbi.nlm.nih.gov/pubmed/30254375
http://dx.doi.org/10.1038/s41418-018-0202-8