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TC2N, a novel oncogene, accelerates tumor progression by suppressing p53 signaling pathway in lung cancer
The protein containing the C2 domain has been well documented for its essential roles in endocytosis, cellular metabolism and cancer. Tac2-N (TC2N) is a tandem C2 domain-containing protein, but its function, including its role in tumorigenesis, remains unknown. Here, we first identified TC2N as a no...
Autores principales: | Hao, Xiang-lin, Han, Fei, Zhang, Ning, Chen, Hong-qiang, Jiang, Xiao, Yin, Li, Liu, Wen-bin, Wang, Dan-dan, Chen, Jian-ping, Cui, Zhi-hong, Ao, Lin, Cao, Jia, Liu, Jin-yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748156/ https://www.ncbi.nlm.nih.gov/pubmed/30254375 http://dx.doi.org/10.1038/s41418-018-0202-8 |
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