Differential gene expression and gene-set enrichment analysis in Caco-2 monolayers during a 30-day timeline with Dexamethasone exposure: A data modeling approach to understanding culture age as co-variate for differential expression in a non-renewing epithelial monolayer using a gene ontology-defined 250-plex Nanostring probe panel.

Glucocorticoid hormones affect gene expression via activation of glucocorticoid receptor NR3C1, causing modulation of inflammation and autoimmune activation. The glucocorticoid Dexamethasone is an important pharmaceutical for the treatment of colitis and other inflammatory bowel diseases. While supp...

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Detalles Bibliográficos
Autores principales: Robinson, J.M., Turkington, S., Abey, S.A., Kenea, N., Henderson, W.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748367/
https://www.ncbi.nlm.nih.gov/pubmed/31438773
http://dx.doi.org/10.1080/21688370.2019.1651597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748367/
https://www.ncbi.nlm.nih.gov/pubmed/31438773
http://dx.doi.org/10.1080/21688370.2019.1651597

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