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Differential gene expression and gene-set enrichment analysis in Caco-2 monolayers during a 30-day timeline with Dexamethasone exposure: A data modeling approach to understanding culture age as co-variate for differential expression in a non-renewing epithelial monolayer using a gene ontology-defined 250-plex Nanostring probe panel.
Glucocorticoid hormones affect gene expression via activation of glucocorticoid receptor NR3C1, causing modulation of inflammation and autoimmune activation. The glucocorticoid Dexamethasone is an important pharmaceutical for the treatment of colitis and other inflammatory bowel diseases. While supp...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748367/ https://www.ncbi.nlm.nih.gov/pubmed/31438773 http://dx.doi.org/10.1080/21688370.2019.1651597 |