The polyether ionophore salinomycin targets multiple cellular pathways to block proliferative vitreoretinopathy pathology

Proliferative vitreoretinopathy (PVR) is characterized by membranes that form in the vitreous cavity and on both surfaces of the retina, which results in the formation of tractional membranes that can cause retinal detachment and intrinsic fibrosis of the retina, leading to retina foreshortening. Cu...

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Detalles Bibliográficos
Autores principales: Heffer, Alison M., Proaño, Jacob, Roztocil, Elisa, Phipps, Richard P., Feldon, Steven E., Huxlin, Krystel R., Sime, Patricia J., Libby, Richard T., Woeller, Collynn F., Kuriyan, Ajay E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748436/
https://www.ncbi.nlm.nih.gov/pubmed/31527897
http://dx.doi.org/10.1371/journal.pone.0222596

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