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ART Attrition across Health Facilities Implementing Option B+ in Haiti

BACKGROUND: Describing factors related to high attrition is important in order to improve the implementation of the Option B+ strategy in Haiti. METHODS: We conducted a retrospective cohort study to describe the variability of antiretroviral therapy (ART) retention across health facilities among pre...

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Autores principales: Myrtil, Martine Pamphile, Puttkammer, Nancy, Gloyd, Stephen, Robinson, Julia, Yuhas, Krista, Domercant, Jean Wysler, Honoré, Jean Guy, Francois, Kesner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748512/
https://www.ncbi.nlm.nih.gov/pubmed/29781378
http://dx.doi.org/10.1177/2325958218774037
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author Myrtil, Martine Pamphile
Puttkammer, Nancy
Gloyd, Stephen
Robinson, Julia
Yuhas, Krista
Domercant, Jean Wysler
Honoré, Jean Guy
Francois, Kesner
author_facet Myrtil, Martine Pamphile
Puttkammer, Nancy
Gloyd, Stephen
Robinson, Julia
Yuhas, Krista
Domercant, Jean Wysler
Honoré, Jean Guy
Francois, Kesner
author_sort Myrtil, Martine Pamphile
collection PubMed
description BACKGROUND: Describing factors related to high attrition is important in order to improve the implementation of the Option B+ strategy in Haiti. METHODS: We conducted a retrospective cohort study to describe the variability of antiretroviral therapy (ART) retention across health facilities among pregnant and lactating women and assess for differences in ART retention between Option B+ clients and other ART patients. RESULTS: There were 1989 Option B+ clients who initiated ART in 45 health facilities. The percentage of attrition varied from 9% to 81% across the facilities. The largest health facilities had 38% higher risk of attrition (relative risk [RR]: 1.38, 95% confidence interval [CI]: 1.08-1.77, P = .009). Private institutions had 18% less risk of attrition (RR: 0.82, 95% CI: 0.70-0.96, P = .020). Health facilities located in the West department and the South region had lower risk of attrition. CONCLUSION: Being on treatment in a large or public health facility or a facility located in the North region was a significant risk factor associated with high attrition among Option B+ clients. The implementation of the Option B+ strategy must be reevaluated in order to effectively eliminate mother-to-child HIV transmission.
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spelling pubmed-67485122019-11-04 ART Attrition across Health Facilities Implementing Option B+ in Haiti Myrtil, Martine Pamphile Puttkammer, Nancy Gloyd, Stephen Robinson, Julia Yuhas, Krista Domercant, Jean Wysler Honoré, Jean Guy Francois, Kesner J Int Assoc Provid AIDS Care Review BACKGROUND: Describing factors related to high attrition is important in order to improve the implementation of the Option B+ strategy in Haiti. METHODS: We conducted a retrospective cohort study to describe the variability of antiretroviral therapy (ART) retention across health facilities among pregnant and lactating women and assess for differences in ART retention between Option B+ clients and other ART patients. RESULTS: There were 1989 Option B+ clients who initiated ART in 45 health facilities. The percentage of attrition varied from 9% to 81% across the facilities. The largest health facilities had 38% higher risk of attrition (relative risk [RR]: 1.38, 95% confidence interval [CI]: 1.08-1.77, P = .009). Private institutions had 18% less risk of attrition (RR: 0.82, 95% CI: 0.70-0.96, P = .020). Health facilities located in the West department and the South region had lower risk of attrition. CONCLUSION: Being on treatment in a large or public health facility or a facility located in the North region was a significant risk factor associated with high attrition among Option B+ clients. The implementation of the Option B+ strategy must be reevaluated in order to effectively eliminate mother-to-child HIV transmission. SAGE Publications 2018-05-20 /pmc/articles/PMC6748512/ /pubmed/29781378 http://dx.doi.org/10.1177/2325958218774037 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Myrtil, Martine Pamphile
Puttkammer, Nancy
Gloyd, Stephen
Robinson, Julia
Yuhas, Krista
Domercant, Jean Wysler
Honoré, Jean Guy
Francois, Kesner
ART Attrition across Health Facilities Implementing Option B+ in Haiti
title ART Attrition across Health Facilities Implementing Option B+ in Haiti
title_full ART Attrition across Health Facilities Implementing Option B+ in Haiti
title_fullStr ART Attrition across Health Facilities Implementing Option B+ in Haiti
title_full_unstemmed ART Attrition across Health Facilities Implementing Option B+ in Haiti
title_short ART Attrition across Health Facilities Implementing Option B+ in Haiti
title_sort art attrition across health facilities implementing option b+ in haiti
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748512/
https://www.ncbi.nlm.nih.gov/pubmed/29781378
http://dx.doi.org/10.1177/2325958218774037
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