Production, characterization, and in vivo half-life extension of polymeric IgA molecules in mice

IgA antibodies have broad potential as a novel therapeutic platform based on their superior receptor-mediated cytotoxic activity, potent neutralization of pathogens, and ability to transcytose across mucosal barriers via polymeric immunoglobulin receptor (pIgR)-mediated transport, compared to tradit...

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Detalles Bibliográficos
Autores principales: Lombana, T. Noelle, Rajan, Sharmila, Zorn, Julie A., Mandikian, Danielle, Chen, Eugene C., Estevez, Alberto, Yip, Victor, Bravo, Daniel D., Phung, Wilson, Farahi, Farzam, Viajar, Sharon, Lee, Sophia, Gill, Avinash, Sandoval, Wendy, Wang, Jianyong, Ciferri, Claudio, Boswell, C. Andrew, Matsumoto, Marissa L., Spiess, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748581/
https://www.ncbi.nlm.nih.gov/pubmed/31122132
http://dx.doi.org/10.1080/19420862.2019.1622940

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