Proteomics and phosphoproteomics study of LCMT1 overexpression and oxidative stress: overexpression of LCMT1 arrests H(2)O(2)-induced lose of cells viability

Objectives: Protein phosphatase 2A (PP2A), a major serine/threonine phosphatase, is also known to be a target of ROS. The methylation of PP2A can be catalyzed by leucine carboxyl methyltransferase-1 (LCMT1), which regulates PP2A activity and substrate specificity. Methods: In the previous study, we...

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Detalles Bibliográficos
Autores principales: Wang, Xinhang, Tang, Shen, Qin, Fu, Liu, Yuyang, Liang, Ziwei, Cai, Haiqing, Mo, Laiming, Xiao, Deqiang, Guo, Songcao, Ouyang, Yiqiang, Sun, Bin, Lu, Cailing, Li, Xiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748586/
https://www.ncbi.nlm.nih.gov/pubmed/30898057
http://dx.doi.org/10.1080/13510002.2019.1595332

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