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Looking for therapeutic antibodies in next-generation sequencing repositories
Recently it has become possible to query the great diversity of natural antibody repertoires using next-generation sequencing (NGS). These methods are capable of producing millions of sequences in a single experiment. Here we compare clinical-stage therapeutic antibodies to the ~1b sequences from 60...
Autores principales: | Krawczyk, Konrad, Raybould, Matthew I. J., Kovaltsuk, Aleksandr, Deane, Charlotte M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748601/ https://www.ncbi.nlm.nih.gov/pubmed/31216939 http://dx.doi.org/10.1080/19420862.2019.1633884 |
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