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Aerobic training reduces oxidative stress in skeletal muscle of rats exposed to air pollution and supplemented with chromium picolinate
Objective: The purpose of this study was to investigate the effects of chromium picolinate (CrPic) supplementation associated with aerobic exercise using measures of oxidative stress in rats exposed to air pollution. Methods: Sixty-one male Wistar rats were divided into eight groups: residual oil fl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748694/ https://www.ncbi.nlm.nih.gov/pubmed/29776315 http://dx.doi.org/10.1080/13510002.2018.1475993 |
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author | Marmett, Bruna Nunes, Ramiro Barcos de Souza, Kellen Sábio Lago, Pedro Dal Rhoden, Cláudia Ramos |
author_facet | Marmett, Bruna Nunes, Ramiro Barcos de Souza, Kellen Sábio Lago, Pedro Dal Rhoden, Cláudia Ramos |
author_sort | Marmett, Bruna |
collection | PubMed |
description | Objective: The purpose of this study was to investigate the effects of chromium picolinate (CrPic) supplementation associated with aerobic exercise using measures of oxidative stress in rats exposed to air pollution. Methods: Sixty-one male Wistar rats were divided into eight groups: residual oil fly ash (ROFA) exposure and sedentary (ROFA-SED); ROFA exposure, sedentary and supplemented (ROFA-SED-CrPic); ROFA exposure and trained (ROFA-AT); ROFA exposure, supplemented and trained (ROFA-AT-CrPic); sedentary (Sal-SED); sedentary and supplemented (Sal-SED-CrPic); trained (Sal-AT); and supplemented and trained (Sal-AT-CrPic). Rats exposed to ROFA (air pollution) received 50 µg of ROFA daily via intranasal instillation. Supplemented rats received CrPic (1 mg/kg/day) daily by oral gavage. Exercise training was performed on a rat treadmill (5×/week). Oxidative parameters were evaluated at the end of protocols. Results: Trained groups demonstrated lower gain of body mass (P < .001) and increased exercise tolerance (P < .0001). In the gastrocnemius, trained groups demonstrated increased SOD activity (P < .0001) and decrease levels of TBARS (P = .0014), although CAT activity did not differ among groups (P = .4487). Conclusion: Air pollution exposure did not lead to alterations in oxidative markers in lungs and heart, and exercise training was responsible for decreasing oxidative stress of the gastrocnemius. |
format | Online Article Text |
id | pubmed-6748694 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-67486942020-04-15 Aerobic training reduces oxidative stress in skeletal muscle of rats exposed to air pollution and supplemented with chromium picolinate Marmett, Bruna Nunes, Ramiro Barcos de Souza, Kellen Sábio Lago, Pedro Dal Rhoden, Cláudia Ramos Redox Rep Research Article Objective: The purpose of this study was to investigate the effects of chromium picolinate (CrPic) supplementation associated with aerobic exercise using measures of oxidative stress in rats exposed to air pollution. Methods: Sixty-one male Wistar rats were divided into eight groups: residual oil fly ash (ROFA) exposure and sedentary (ROFA-SED); ROFA exposure, sedentary and supplemented (ROFA-SED-CrPic); ROFA exposure and trained (ROFA-AT); ROFA exposure, supplemented and trained (ROFA-AT-CrPic); sedentary (Sal-SED); sedentary and supplemented (Sal-SED-CrPic); trained (Sal-AT); and supplemented and trained (Sal-AT-CrPic). Rats exposed to ROFA (air pollution) received 50 µg of ROFA daily via intranasal instillation. Supplemented rats received CrPic (1 mg/kg/day) daily by oral gavage. Exercise training was performed on a rat treadmill (5×/week). Oxidative parameters were evaluated at the end of protocols. Results: Trained groups demonstrated lower gain of body mass (P < .001) and increased exercise tolerance (P < .0001). In the gastrocnemius, trained groups demonstrated increased SOD activity (P < .0001) and decrease levels of TBARS (P = .0014), although CAT activity did not differ among groups (P = .4487). Conclusion: Air pollution exposure did not lead to alterations in oxidative markers in lungs and heart, and exercise training was responsible for decreasing oxidative stress of the gastrocnemius. Taylor & Francis 2018-05-18 /pmc/articles/PMC6748694/ /pubmed/29776315 http://dx.doi.org/10.1080/13510002.2018.1475993 Text en © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Marmett, Bruna Nunes, Ramiro Barcos de Souza, Kellen Sábio Lago, Pedro Dal Rhoden, Cláudia Ramos Aerobic training reduces oxidative stress in skeletal muscle of rats exposed to air pollution and supplemented with chromium picolinate |
title | Aerobic training reduces oxidative stress in skeletal muscle of rats
exposed to air pollution and supplemented with chromium
picolinate |
title_full | Aerobic training reduces oxidative stress in skeletal muscle of rats
exposed to air pollution and supplemented with chromium
picolinate |
title_fullStr | Aerobic training reduces oxidative stress in skeletal muscle of rats
exposed to air pollution and supplemented with chromium
picolinate |
title_full_unstemmed | Aerobic training reduces oxidative stress in skeletal muscle of rats
exposed to air pollution and supplemented with chromium
picolinate |
title_short | Aerobic training reduces oxidative stress in skeletal muscle of rats
exposed to air pollution and supplemented with chromium
picolinate |
title_sort | aerobic training reduces oxidative stress in skeletal muscle of rats
exposed to air pollution and supplemented with chromium
picolinate |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748694/ https://www.ncbi.nlm.nih.gov/pubmed/29776315 http://dx.doi.org/10.1080/13510002.2018.1475993 |
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