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Renal mitochondrial oxidative stress is enhanced by the reduction of Sirt3 activity, in Zucker diabetic fatty rats

Objectives: Mitochondrial oxidative stress is involved in the pathogenesis of diabetic kidney disease. The objective of our study is to identify the mechanisms of renal mitochondrial oxidative stress, focusing on Sirt3, which is nicotinamide adenine dinucleotide (NAD(+); oxidized NAD)-dependent deac...

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Detalles Bibliográficos
Autores principales: Ogura, Yoshio, Kitada, Munehiro, Monno, Itaru, Kanasaki, Keizo, Watanabe, Ai, Koya, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748695/
https://www.ncbi.nlm.nih.gov/pubmed/29897845
http://dx.doi.org/10.1080/13510002.2018.1487174