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Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes

MOTIVATION: Medulloblastoma (MB) is a brain cancer predominantly arising in children. Roughly 70% of patients are cured today, but survivors often suffer from severe sequelae. MB has been extensively studied by molecular profiling, but often in small and scattered cohorts. To improve cure rates and...

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Detalles Bibliográficos
Autores principales: Weishaupt, Holger, Johansson, Patrik, Sundström, Anders, Lubovac-Pilav, Zelmina, Olsson, Björn, Nelander, Sven, Swartling, Fredrik J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748729/
https://www.ncbi.nlm.nih.gov/pubmed/30715209
http://dx.doi.org/10.1093/bioinformatics/btz066