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Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes
MOTIVATION: Medulloblastoma (MB) is a brain cancer predominantly arising in children. Roughly 70% of patients are cured today, but survivors often suffer from severe sequelae. MB has been extensively studied by molecular profiling, but often in small and scattered cohorts. To improve cure rates and...
Autores principales: | Weishaupt, Holger, Johansson, Patrik, Sundström, Anders, Lubovac-Pilav, Zelmina, Olsson, Björn, Nelander, Sven, Swartling, Fredrik J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748729/ https://www.ncbi.nlm.nih.gov/pubmed/30715209 http://dx.doi.org/10.1093/bioinformatics/btz066 |
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