Cargando…

Modeling cell proliferation in human acute myeloid leukemia xenografts

MOTIVATION: Acute myeloid leukemia (AML) is one of the most common hematological malignancies, characterized by high relapse and mortality rates. The inherent intra-tumor heterogeneity in AML is thought to play an important role in disease recurrence and resistance to chemotherapy. Although experime...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nobile, Marco S, Vlachou, Thalia, Spolaor, Simone, Bossi, Daniela, Cazzaniga, Paolo, Lanfrancone, Luisa, Mauri, Giancarlo, Pelicci, Pier Giuseppe, Besozzi, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748761/ https://www.ncbi.nlm.nih.gov/pubmed/30753298 http://dx.doi.org/10.1093/bioinformatics/btz063

Ejemplares similares

Barcode demultiplexing of nanopore sequencing raw signals by unsupervised machine learning
por: Papetti, Daniele M., et al.
Publicado: (2023)

Surfing on Fitness Landscapes: A Boost on Optimization by Fourier Surrogate Modeling
por: Manzoni, Luca, et al.
Publicado: (2020)

FiCoS: A fine-grained and coarse-grained GPU-powered deterministic simulator for biochemical networks
por: Tangherloni, Andrea, et al.
Publicado: (2021)

GenHap: a novel computational method based on genetic algorithms for haplotype assembly
por: Tangherloni, Andrea, et al.
Publicado: (2019)

Screening for Combination Cancer Therapies With Dynamic Fuzzy Modeling and Multi-Objective Optimization
por: Spolaor, Simone, et al.
Publicado: (2021)

Modeling Calcium Signaling in S. cerevisiae Highlights the Role and Regulation of the Calmodulin-Calcineurin Pathway in Response to Hypotonic Shock
por: Spolaor, Simone, et al.
Publicado: (2022)

Massive Exploration of Perturbed Conditions of the Blood Coagulation Cascade through GPU Parallelization
por: Cazzaniga, Paolo, et al.
Publicado: (2014)

cuTauLeaping: A GPU-Powered Tau-Leaping Stochastic Simulator for Massive Parallel Analyses of Biological Systems
por: Nobile, Marco S., et al.
Publicado: (2014)

LASSIE: simulating large-scale models of biochemical systems on GPUs
por: Tangherloni, Andrea, et al.
Publicado: (2017)

Fuzzy modeling and global optimization to predict novel therapeutic targets in cancer cells
por: Nobile, Marco S, et al.
Publicado: (2020)

ACDC: Automated Cell Detection and Counting for Time-Lapse Fluorescence Microscopy
por: Rundo, Leonardo, et al.
Publicado: (2020)

Graphics processing units in bioinformatics, computational biology and systems biology
por: Nobile, Marco S, et al.
Publicado: (2017)

Regulation of LncRNAs in Melanoma and Their Functional Roles in the Metastatic Process
por: Melixetian, Marine, et al.
Publicado: (2022)

HyperBeta: characterizing the structural dynamics of proteins and self-assembling peptides
por: Nobile, Marco S., et al.
Publicado: (2021)

Computational Strategies for a System-Level Understanding of Metabolism
por: Cazzaniga, Paolo, et al.
Publicado: (2014)

The role of feedback control mechanisms on the establishment of oscillatory regimes in the Ras/cAMP/PKA pathway in S. cerevisiae
por: Besozzi, Daniela, et al.
Publicado: (2012)

GPU-powered model analysis with PySB/cupSODA
por: Harris, Leonard A, et al.
Publicado: (2017)

Genomics of Acute Myeloid Leukemia: The Next Generation
por: Riva, Laura, et al.
Publicado: (2012)

RNAi screens identify CHD4 as an essential gene in breast cancer growth
por: D'Alesio, Carolina, et al.
Publicado: (2016)

WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells
por: Punzi, Simona, et al.
Publicado: (2019)

Long non‐coding RNA TINCR suppresses metastatic melanoma dissemination by preventing ATF4 translation
por: Melixetian, Marine, et al.
Publicado: (2021)

Human cord blood (hCB)-CD34(+) humanized mice fail to reject human acute myeloid leukemia cells
por: Tanaskovic, Olga, et al.
Publicado: (2019)

Development of Personalized Therapeutic Strategies by Targeting Actionable Vulnerabilities in Metastatic and Chemotherapy-Resistant Breast Cancer PDXs
por: Punzi, Simona, et al.
Publicado: (2019)

p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value
por: Santoro, Angela, et al.
Publicado: (2019)

XenoCell: classification of cellular barcodes in single cell experiments from xenograft samples
por: Cheloni, Stefano, et al.
Publicado: (2021)

Acute myeloid leukemia xenograft success prediction: Saving time
por: Griessinger, Emmanuel, et al.
Publicado: (2018)

The Multi-Level Mechanism of Action of a Pan-Ras Inhibitor Explains its Antiproliferative Activity on Cetuximab-Resistant Cancer Cells
por: Tisi, Renata, et al.
Publicado: (2021)

Single-Cell Technologies to Decipher the Immune Microenvironment in Myeloid Neoplasms: Perspectives and Opportunities
por: Caprioli, Chiara, et al.
Publicado: (2022)

A Graph Theory Approach to Fuzzy Rule Base Simplification
por: Fuchs, Caro, et al.
Publicado: (2020)

Corrigendum: Single-cell technologies to decipher the immune microenvironment in myeloid neoplasms: Perspectives and opportunities
por: Caprioli, Chiara, et al.
Publicado: (2022)

Modeling of Chronic Myeloid Leukemia: An Overview of In Vivo Murine and Human Xenograft Models
por: Sontakke, Pallavi, et al.
Publicado: (2016)

Murine models based on acute myeloid leukemia-initiating stem cells xenografting
por: Mambet, Cristina, et al.
Publicado: (2018)

Selected papers from the 15th and 16th international conference on Computational Intelligence Methods for Bioinformatics and Biostatistics
por: Cazzaniga, Paolo, et al.
Publicado: (2021)

Imetelstat Induces Leukemia Stem Cell Death in Pediatric Acute Myeloid Leukemia Patient-Derived Xenografts
por: Barwe, Sonali P., et al.
Publicado: (2022)

Correlative Multi-Modal Microscopy: A Novel Pipeline for Optimizing Fluorescence Microscopy Resolutions in Biological Applications
por: Pelicci, Simone, et al.
Publicado: (2023)

In vivo and in silico analysis of PCNA ubiquitylation in the activation of the Post Replication Repair pathway in S. cerevisiae
por: Amara, Flavio, et al.
Publicado: (2013)

Reduced Expression of Sprouty1 Contributes to the Aberrant Proliferation and Impaired Apoptosis of Acute Myeloid Leukemia Cells
por: Rosso, Valentina, et al.
Publicado: (2019)

Chromosomal rearrangements in acute myeloid leukemia (AML)
por: Belloni, E, et al.
Publicado: (2010)

Checkpoint Inhibitors in Acute Myeloid Leukemia
por: Damiani, Daniela, et al.
Publicado: (2023)

From Double-Strand Break Recognition to Cell-Cycle Checkpoint Activation: High Content and Resolution Image Cytometry Unmasks 53BP1 Multiple Roles in DNA Damage Response and p53 Action
por: Furia, Laura, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_giq3e3goi11f5blmjp35sst6h4