PROSSTT: probabilistic simulation of single-cell RNA-seq data for complex differentiation processes

SUMMARY: Cellular lineage trees can be derived from single-cell RNA sequencing snapshots of differentiating cells. Currently, only datasets with simple topologies are available. To test and further develop tools for lineage tree reconstruction, we need test datasets with known complex topologies. PR...

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Detalles Bibliográficos
Autores principales: Papadopoulos, Nikolaos, Gonzalo, Parra R, Söding, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748774/
https://www.ncbi.nlm.nih.gov/pubmed/30715210
http://dx.doi.org/10.1093/bioinformatics/btz078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748774/
https://www.ncbi.nlm.nih.gov/pubmed/30715210
http://dx.doi.org/10.1093/bioinformatics/btz078

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