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PROSSTT: probabilistic simulation of single-cell RNA-seq data for complex differentiation processes
SUMMARY: Cellular lineage trees can be derived from single-cell RNA sequencing snapshots of differentiating cells. Currently, only datasets with simple topologies are available. To test and further develop tools for lineage tree reconstruction, we need test datasets with known complex topologies. PR...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748774/ https://www.ncbi.nlm.nih.gov/pubmed/30715210 http://dx.doi.org/10.1093/bioinformatics/btz078 |