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How well do RNA-Seq differential gene expression tools perform in a complex eukaryote? A case study in Arabidopsis thaliana

MOTIVATION: RNA-seq experiments are usually carried out in three or fewer replicates. In order to work well with so few samples, differential gene expression (DGE) tools typically assume the form of the underlying gene expression distribution. In this paper, the statistical properties of gene expres...

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Detalles Bibliográficos
Autores principales:	Froussios, Kimon, Schurch, Nick J, Mackinnon, Katarzyna, Gierliński, Marek, Duc, Céline, Simpson, Gordon G, Barton, Geoffrey J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748783/ https://www.ncbi.nlm.nih.gov/pubmed/30726870 http://dx.doi.org/10.1093/bioinformatics/btz089

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