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Single molecule mechanics resolves the earliest events in force generation by cardiac myosin
Key steps of cardiac mechanochemistry, including the force-generating working stroke and the release of phosphate (P(i)), occur rapidly after myosin-actin attachment. An ultra-high-speed optical trap enabled direct observation of the timing and amplitude of the working stroke, which can occur within...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748826/ https://www.ncbi.nlm.nih.gov/pubmed/31526481 http://dx.doi.org/10.7554/eLife.49266 |