Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer’s disease

Studies of rodent models of Alzheimer’s disease (AD) and of human tissues suggest that the retinal changes that occur in AD, including the accumulation of amyloid beta (Aβ), may serve as surrogate markers of brain Aβ levels. As Aβ has a wavelength-dependent effect on light scatter, we investigate th...

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Detalles Bibliográficos
Autores principales: Hadoux, Xavier, Hui, Flora, Lim, Jeremiah K. H., Masters, Colin L., Pébay, Alice, Chevalier, Sophie, Ha, Jason, Loi, Samantha, Fowler, Christopher J., Rowe, Christopher, Villemagne, Victor L., Taylor, Edward N., Fluke, Christopher, Soucy, Jean-Paul, Lesage, Frédéric, Sylvestre, Jean-Philippe, Rosa-Neto, Pedro, Mathotaarachchi, Sulantha, Gauthier, Serge, Nasreddine, Ziad S., Arbour, Jean Daniel, Rhéaume, Marc-André, Beaulieu, Sylvain, Dirani, Mohamed, Nguyen, Christine T. O., Bui, Bang V., Williamson, Robert, Crowston, Jonathan G., van Wijngaarden, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748929/
https://www.ncbi.nlm.nih.gov/pubmed/31530809
http://dx.doi.org/10.1038/s41467-019-12242-1

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