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Tumor Infiltrating Lymphocytes and Macrophages Improve Survival in Microsatellite Unstable Colorectal Cancer

Due to the loss of DNA repair mechanisms in colorectal cancer (CRC) with microsatellite instability (MSI), somatic mutations accumulate within DNA; making them more prone to attack by tumor infiltrating lymphocytes (TIL) and macrophages. We hypothesize that MSI-High (MSI-H) patients have favorable s...

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Detalles Bibliográficos
Autores principales:	Narayanan, Sumana, Kawaguchi, Tsutomu, Peng, Xuan, Qi, Qianya, Liu, Song, Yan, Li, Takabe, Kazuaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748965/ https://www.ncbi.nlm.nih.gov/pubmed/31530839 http://dx.doi.org/10.1038/s41598-019-49878-4

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