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Overexpression of p16(INK4a) Serves as Prognostic Marker in Squamous Cell Vulvar Cancer Patients Treated With Radiotherapy Irrespective of HPV-Status

Purpose: We aimed to evaluate the impact of HPV-driven carcinogenesis on outcome in vulvar squamous cell carcinoma patients (VSCC) treated with radiotherapy. Methods and Materials: Analysis of clinical, pathological, and treatment data, HPV DNA-detection and -genotyping as well as p16(INK4a) immunoh...

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Detalles Bibliográficos
Autores principales: Arians, Nathalie, Prigge, Elena-Sophie, Nachtigall, Tereza, Reuschenbach, Miriam, Koerber, Stefan Alexander, Debus, Juergen, von Knebel Doeberitz, Magnus, Lindel, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749023/
https://www.ncbi.nlm.nih.gov/pubmed/31572682
http://dx.doi.org/10.3389/fonc.2019.00891