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Mst1-Deficiency Induces Hyperactivation of Monocyte-Derived Dendritic Cells via Akt1/c-myc Pathway
Mst1 is a multifunctional serine/threonine kinase that is highly expressed in several immune organs. The role of Mst1 in the activation of dendritic cells (DCs), a key player of adaptive immunity, is poorly understood. In this study, we investigated the role of Mst1 in GM-CSF-induced bone marrow-der...
Autores principales: | Cho, Kyung-Min, Kim, Myun Soo, Jung, Hak-Jun, Choi, Eui-Ju, Kim, Tae Sung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749027/ https://www.ncbi.nlm.nih.gov/pubmed/31572367 http://dx.doi.org/10.3389/fimmu.2019.02142 |
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