Cargando…

Apigenin Inhibits IL-6 Transcription and Suppresses Esophageal Carcinogenesis

Esophagus cancer is the seventh cause of cancer-related deaths globally. In this study, we analyzed interleukin 6 (IL-6) gene expression in human esophagus cancer patients and showed that IL-6 mRNA levels are significantly higher in tumor tissues and negatively correlated with overall survival, sugg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qiu, Jian-Ge, Wang, Lin, Liu, Wen-Jing, Wang, Ju-Feng, Zhao, Er-Jiang, Zhou, Feng-Mei, Ji, Xiang-Bo, Wang, Li-Hong, Xia, Zhong-Kun, Wang, Wei, Lin, Marie Chia-mi, Liu, Ling-Zhi, Huang, Ying-Xue, Jiang, Bing-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749068/ https://www.ncbi.nlm.nih.gov/pubmed/31572184 http://dx.doi.org/10.3389/fphar.2019.01002

Ejemplares similares

Evodiamine, a Novel NOTCH3 Methylation Stimulator, Significantly Suppresses Lung Carcinogenesis in Vitro and in Vivo
por: Su, Tao, et al.
Publicado: (2018)

Effects of Apigenin Treatment on Random Skin Flap Survival in Rats
por: Ma, Xinyi, et al.
Publicado: (2021)

Apigenin Alleviates Autoimmune Uveitis by Inhibiting Microglia M1 Pro-Inflammatory Polarization
por: Shu, Nan, et al.
Publicado: (2023)

Apigenin Prevents Acetaminophen-Induced Liver Injury by Activating the SIRT1 Pathway
por: Zhao, Licong, et al.
Publicado: (2020)

Inhibitory Effects of Apigenin on Tumor Carcinogenesis by Altering the Gut Microbiota
por: Bian, Shichang, et al.
Publicado: (2020)

A Mini-Review of Flavone Isomers Apigenin and Genistein in Prostate Cancer Treatment
por: Ji, Xiaozhen, et al.
Publicado: (2022)

Apigenin Attenuates the Allergic Reactions by Competitively Binding to ER With Estradiol
por: Yao, Lu, et al.
Publicado: (2020)

Suppression of Esophageal Cancer Stem-like Cells by SNX-2112 Is Enhanced by STAT3 Silencing
por: Xu, Dan-dan, et al.
Publicado: (2020)

Anthocyanin Protects Cardiac Function and Cardiac Fibroblasts From High-Glucose Induced Inflammation and Myocardial Fibrosis by Inhibiting IL-17
por: Yue, Er, et al.
Publicado: (2021)

Apigenin inhibits growth and migration of fibroblasts by suppressing FAK signaling
por: Wang, Hongyi, et al.
Publicado: (2019)

In Vitro and In Vivo Anti-tumoral Effects of the Flavonoid Apigenin in Malignant Mesothelioma
por: Masuelli, Laura, et al.
Publicado: (2017)

Apigenin, a Single Active Component of Herbal Extract, Alleviates Xerostomia via ERα-Mediated Upregulation of AQP5 Activation
por: Wei, Wei, et al.
Publicado: (2022)

Nuclear Magnetic Resonance-Based Metabolomics Approach to Evaluate the Prevention Effect of Camellia nitidissima Chi on Colitis-Associated Carcinogenesis
por: Li, Ming-Hui, et al.
Publicado: (2017)

EGFR-IL-6 Signaling Axis Mediated the Inhibitory Effect of Methylseleninic Acid on Esophageal Squamous Cell Carcinoma
por: Wang, Yu, et al.
Publicado: (2021)

The genome sequence of celery (Apium graveolens L.), an important leaf vegetable crop rich in apigenin in the Apiaceae family
por: Li, Meng-Yao, et al.
Publicado: (2020)

Apigenin Attenuates Acetaminophen-Induced Hepatotoxicity by Activating AMP-Activated Protein Kinase/Carnitine Palmitoyltransferase I Pathway
por: Zhang, Jiaqi, et al.
Publicado: (2020)

Nobiletin Inhibits IL-1β-Induced Inflammation in Chondrocytes via Suppression of NF-κB Signaling and Attenuates Osteoarthritis in Mice
por: Lin, Zeng, et al.
Publicado: (2019)

Inhibition of WEE1 Suppresses the Tumor Growth in Laryngeal Squamous Cell Carcinoma
por: Yuan, Meng-Ling, et al.
Publicado: (2018)

Apigenin inhibits renal cell carcinoma cell proliferation
por: Meng, Shuai, et al.
Publicado: (2017)

Does Oral Apigenin Have Real Potential for a Therapeutic Effect in the Context of Human Gastrointestinal and Other Cancers?
por: DeRango-Adem, Eva F., et al.
Publicado: (2021)

Apigenin directly interacts with and inhibits topoisomerase 1 to upregulate CD26/DPP4 on colorectal carcinoma cells
por: Fux, Julia E., et al.
Publicado: (2022)

Suppression of CD13 Enhances the Cytotoxic Effect of Chemotherapeutic Drugs in Hepatocellular Carcinoma Cells
por: Ji, Shengping, et al.
Publicado: (2021)

IL-9 neutralizing antibody suppresses allergic inflammation in ovalbumin-induced allergic rhinitis mouse model
por: Zhao, He, et al.
Publicado: (2022)

Reactivation of mutant p53 in esophageal squamous cell carcinoma by isothiocyanate inhibits tumor growth
por: Guan, Lulu, et al.
Publicado: (2023)

Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis
por: Ye, Bo, et al.
Publicado: (2021)

Chang qing formula ameliorates colitis-associated colorectal cancer via suppressing IL-17/NF-κB/STAT3 pathway in mice as revealed by network pharmacology study
por: Luo, Qihan, et al.
Publicado: (2022)

Apigenin and Luteolin Attenuate the Breaching of MDA-MB231 Breast Cancer Spheroids Through the Lymph Endothelial Barrier in Vitro
por: Hong, Junli, et al.
Publicado: (2018)

Polyporus Polysaccharide Ameliorates Bleomycin-Induced Pulmonary Fibrosis by Suppressing Myofibroblast Differentiation via TGF-β/Smad2/3 Pathway
por: Jiang, Jintao, et al.
Publicado: (2020)

Yanghe Decoction Suppresses the Experimental Autoimmune Thyroiditis in Rats by Improving NLRP3 Inflammasome and Immune Dysregulation
por: Ma, Bing’e, et al.
Publicado: (2021)

Metabolomics profiling of AKT/c-Met-induced hepatocellular carcinogenesis and the inhibitory effect of Cucurbitacin B in mice
por: Ji, Xiangyu, et al.
Publicado: (2022)

Over-Expression of Inhibitor of Differentiation 2 Attenuates Post-Infarct Cardiac Fibrosis Through Inhibition of TGF-β1/Smad3/HIF-1α/IL-11 Signaling Pathway
por: Yin, Lin, et al.
Publicado: (2019)

Antitumor and Anti-Invasive Effect of Apigenin on Human Breast Carcinoma through Suppression of IL-6 Expression
por: Lee, Hwan Hee, et al.
Publicado: (2019)

Discovery of a New CDK4/6 and PI3K/AKT Multiple Kinase Inhibitor Aminoquinol for the Treatment of Hepatocellular Carcinoma
por: Xia, Zhong-Kun, et al.
Publicado: (2021)

Emerging Biological Functions of IL-17A: A New Target in Chronic Obstructive Pulmonary Disease?
por: Liu, Meiling, et al.
Publicado: (2021)

Framework Development for Clinical Comprehensive Evaluation of Drugs–a Study Protocol Using the Delphi Method and Analytic Hierarchy Process
por: Zhang, Chi, et al.
Publicado: (2022)

UDCA Inhibits Hypoxic Hepatocellular Carcinoma Cell–Induced Angiogenesis Through Suppressing HIF-1α/VEGF/IL-8 Intercellular Signaling
por: Lin, Wanfu, et al.
Publicado: (2021)

Tp53 Mutation Inhibits Ubiquitination and Degradation of WISP1 via Down-Regulation of Siah1 in Pancreatic Carcinogenesis
por: Wu, Wei, et al.
Publicado: (2018)

Apigenin Inhibits UVB-Induced Skin Carcinogenesis: The Role of Thrombospondin-1 as an Anti-Inflammatory Factor
por: Mirzoeva, Salida, et al.
Publicado: (2018)

Punicalagin Alleviates Psoriasis by Inhibiting NF-κB-Mediated IL-1β Transcription and Caspase-1-Regulated IL-1β Secretion
por: Tang, Lipeng, et al.
Publicado: (2022)

EGCG protects the mouse brain against cerebral ischemia/reperfusion injury by suppressing autophagy via the AKT/AMPK/mTOR phosphorylation pathway
por: Wang, Li, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_cd3n6p73lco4t4las205th5lc2