Detrimental Effect of Type I IFNs During Acute Lung Infection With Pseudomonas aeruginosa Is Mediated Through the Stimulation of Neutrophil NETosis

Pseudomonas aeruginosa is an opportunistic multidrug-resistant pathogen, able to grow in biofilms. It causes life-threatening complications in diseases characterized by the up-regulation of type I interferon (IFN) signaling, such as cancer or viral infections. Since type I IFNs regulate multiple fun...

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Detalles Bibliográficos
Autores principales: Pylaeva, Ekaterina, Bordbari, Sharareh, Spyra, Ilona, Decker, Anna Sophie, Häussler, Susanne, Vybornov, Vadim, Lang, Stephan, Jablonska, Jadwiga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749149/
https://www.ncbi.nlm.nih.gov/pubmed/31572395
http://dx.doi.org/10.3389/fimmu.2019.02190

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