Association between cardiovascular risk factors and triglyceride to high-density lipoprotein ratio: a single-center experience

INTRODUCTION: We aimed to investigate associations between triglycerides (Tg)/high-density lipoprotein (HDL) and age, body mass index (BMI), waist circumference (WC), systolic and diastolic blood pressure (SBP, DBP), fasting blood glucose (FBG), and smoking in patients without diabetes mellitus. MATERIAL AND METHODS: The study included 91 patients between 18 and 65 years old age, with no diagnosis of diabetes mellitus. Laboratory parameters of Tg, low-density lipoprotein (LDL), HDL cholesterol, FBG, BMI (kg/m(2)), WC (cm), SBP and DBP (mm Hg), smoking status, and demographic data were collected from patients’ electronic records. Patients whose Tg/HDL was under 3 were grouped as group A; those whose ratio was over 3 were grouped as group B. RESULTS: The mean age, BMI, WC, SBP, and DBP were higher in the group in which Tg/HDL was higher. Although total cigarette exposure and FBG were higher in group B, the difference between the 2 groups was not statistically significant. Tg/HDL was positively correlated with BMI and positively correlated with WC in correlation analyses. It was observed that every 1-point increase in BMI caused a 0.1-point increase in Tg/HDL and smoking caused a 1.09-point increase in Tg/HDL in multivariate regression analysis. CONCLUSIONS: The WC, BMI, SBP, and DBP are higher in the group in which Tg/HDL is higher. Further, high BMI and smoking are also related to high Tg/HDL in our study. Key words: smoking, body mass index, triglyceride, waist circumference, HDL cholesterol.