Cargando…

DMPK is a New Candidate Mediator of Tumor Suppressor p53-Dependent Cell Death

Tumor suppressor p53 plays an integral role in DNA-damage induced apoptosis, a biological process that protects against tumor progression. Cell shape dramatically changes when cells undergo apoptosis, which is associated with actomyosin contraction; however, it remains entirely elusive how p53 regul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Itoh, Katsuhiko, Ebata, Takahiro, Hirata, Hiroaki, Torii, Takeru, Sugimoto, Wataru, Onodera, Keigo, Nakajima, Wataru, Uehara, Ikuno, Okuzaki, Daisuke, Yamauchi, Shota, Budirahardja, Yemima, Nishikata, Takahito, Tanaka, Nobuyuki, Kawauchi, Keiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749264/ https://www.ncbi.nlm.nih.gov/pubmed/31480541 http://dx.doi.org/10.3390/molecules24173175

Ejemplares similares

Loss of p53 function promotes DNA damage-induced formation of nuclear actin filaments
por: Torii, Takeru, et al.
Publicado: (2023)

MMP24 as a Target of YAP Is a Potential Prognostic Factor in Cancer Patients
por: Sugimoto, Wataru, et al.
Publicado: (2020)

Substrate Stiffness Influences Doxorubicin-Induced p53 Activation via ROCK2 Expression
por: Ebata, Takahiro, et al.
Publicado: (2017)

Glycosyl Phosphatidylinositol Anchor Biosynthesis Is Essential for Maintaining Epithelial Integrity during Caenorhabditis elegans Embryogenesis
por: Budirahardja, Yemima, et al.
Publicado: (2015)

Functions of the Tumor Suppressors p53 and Rb in Actin Cytoskeleton Remodeling
por: Ebata, Takahiro, et al.
Publicado: (2016)

p53-mediated activation of the mitochondrial protease HtrA2/Omi prevents cell invasion
por: Yamauchi, Shota, et al.
Publicado: (2014)

Mitochondrial protein E2F3d, a distinctive E2F3 product, mediates hypoxia-induced mitophagy in cancer cells
por: Araki, Keigo, et al.
Publicado: (2019)

An anionic phthalocyanine decreases NRAS expression by breaking down its RNA G-quadruplex
por: Kawauchi, Keiko, et al.
Publicado: (2018)

Expanded DMPK repeats in dizygotic twins referred for diagnosis of autism versus absence of expanded DMPK repeats at screening of 330 children with autism
por: Musova, Zuzana, et al.
Publicado: (2016)

The AP-2 Transcription Factor APTF-2 Is Required for Neuroblast and Epidermal Morphogenesis in Caenorhabditis elegans Embryogenesis
por: Budirahardja, Yemima, et al.
Publicado: (2016)

Epigenetics of the myotonic dystrophy-associated DMPK gene neighborhood
por: Buckley, Lauren, et al.
Publicado: (2016)

Anti-Malignant Effect of Tensile Loading to Adherens Junctions in Cutaneous Squamous Cell Carcinoma Cells
por: Dobrokhotov, Oleg, et al.
Publicado: (2021)

Cooperation meets competition in microRNA-mediated DMPK transcript regulation
por: Koscianska, Edyta, et al.
Publicado: (2015)

DMPK mRNA Expression in Human Brain Tissue Throughout the Lifespan
por: Langbehn, Kathleen E., et al.
Publicado: (2020)

DMPK hypermethylation in sperm cells of myotonic dystrophy type 1 patients
por: Yanovsky-Dagan, Shira, et al.
Publicado: (2021)

Role of p53 in the Regulation of the Inflammatory Tumor Microenvironment and Tumor Suppression
por: Uehara, Ikuno, et al.
Publicado: (2018)

Cytoplasmic translocation of the retinoblastoma protein disrupts sarcomeric organization
por: Araki, Keigo, et al.
Publicado: (2013)

Role of Myotonic Dystrophy Protein Kinase (DMPK) in Glucose Homeostasis and Muscle Insulin Action
por: Llagostera, Esther, et al.
Publicado: (2007)

Sense and Antisense DMPK RNA Foci Accumulate in DM1 Tissues during Development
por: Michel, Lise, et al.
Publicado: (2015)

DMPK gene DNA methylation levels are associated with muscular and respiratory profiles in DM1
por: Légaré, Cécilia, et al.
Publicado: (2019)

High Resolution Analysis of DMPK Hypermethylation and Repeat Interruptions in Myotonic Dystrophy Type 1
por: Rasmussen, Astrid, et al.
Publicado: (2022)

Non-Alcoholic Steatohepatitis in Myotonic Dystrophy: DMPK Gene Mutation, Insulin Resistance and Development of Steatohepatitis
por: Bhardwaj, Rishi R., et al.
Publicado: (2010)

Targeting DMPK with Antisense Oligonucleotide Improves Muscle Strength in Myotonic Dystrophy Type 1 Mice
por: Jauvin, Dominic, et al.
Publicado: (2017)

Antiparasitic Sesquiterpenes from the Cameroonian Spice Scleria striatinux and Preliminary In Vitro and In Silico DMPK Assessment
por: Nyongbela, Kennedy D., et al.
Publicado: (2017)

Variant repeats within the DMPK CTG expansion protect function in myotonic dystrophy type 1
por: Miller, Jacob N., et al.
Publicado: (2020)

Actin Filament in the First Cell Cycle Contributes to the Determination of the Anteroposterior Axis in Ascidian Development
por: Goto, Toshiyuki, et al.
Publicado: (2022)

Photosensitizers Based on G-Quadruplex Ligand for Cancer Photodynamic Therapy
por: Kawauchi, Keiko, et al.
Publicado: (2020)

Muscular myopathies other than myotonic dystrophy also associated with (CTG)(n) expansion at the DMPK locus
por: Mohan, Vasavi, et al.
Publicado: (2012)

Dynamic changes in the association between maternal mRNAs and endoplasmic reticulum during ascidian early embryogenesis
por: Goto, Toshiyuki, et al.
Publicado: (2021)

Association between tensin 1 and p130Cas at focal adhesions links actin inward flux to cell migration
por: Zhao, Zhihai, et al.
Publicado: (2016)

DDX6 regulates sequestered nuclear CUG-expanded DMPK-mRNA in dystrophia myotonica type 1
por: Pettersson, Olof J., et al.
Publicado: (2014)

Expanded CUG repeats in DMPK transcripts adopt diverse hairpin conformations without influencing the structure of the flanking sequences
por: van Cruchten, Remco T.P., et al.
Publicado: (2019)

Repeat Interruptions Modify Age at Onset in Myotonic Dystrophy Type 1 by Stabilizing DMPK Expansions in Somatic Cells
por: Pešović, Jovan, et al.
Publicado: (2018)

Robust and accurate detection and sizing of repeats within the DMPK gene using a novel TP-PCR test
por: Leferink, Maike, et al.
Publicado: (2019)

Time-controlled and muscle-specific CRISPR/Cas9-mediated deletion of CTG-repeat expansion in the DMPK gene
por: Cardinali, Beatrice, et al.
Publicado: (2021)

Can remdesivir and its parent nucleoside GS-441524 be potential oral drugs? An in vitro and in vivo DMPK assessment
por: Xie, Jiashu, et al.
Publicado: (2021)

Data on the solution and processing time reached when constructing a phylogenetic tree using a quantum-inspired computer
por: Onodera, Wataru, et al.
Publicado: (2023)

Cochlear supporting cells function as macrophage-like cells and protect audiosensory receptor hair cells from pathogens
por: Hayashi, Yushi, et al.
Publicado: (2020)

Virus-infection in cochlear supporting cells induces audiosensory receptor hair cell death by TRAIL-induced necroptosis
por: Hayashi, Yushi, et al.
Publicado: (2021)

Mutant DMPK 3′-UTR transcripts disrupt C2C12 myogenic differentiation by compromising MyoD
por: Amack, Jeffrey D., et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_6be9h8cfeagtac531mobg9lgp5