Cargando…

Antibacterial Evaluation, In Silico Characters and Molecular Docking of Schiff Bases Derived from 5-aminopyrazoles

A series of Schiff bases 14–25 were designed and synthesized for evaluation of their antibacterial properties against multi-drug resistant bacteria (MDRB). The antibacterial activities of Schiff bases 14–25 showed that most of the synthesized compounds displayed a significant antibacterial activity....

Descripción completa

Detalles Bibliográficos
Autores principales:	Hassan, Ashraf S., Askar, Ahmed A., Nossier, Eman S., Naglah, Ahmed M., Moustafa, Gaber O., Al-Omar, Mohamed A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749370/ https://www.ncbi.nlm.nih.gov/pubmed/31466322 http://dx.doi.org/10.3390/molecules24173130

Ejemplares similares

Discovery of New Schiff Bases Tethered Pyrazole Moiety: Design, Synthesis, Biological Evaluation, and Molecular Docking Study as Dual Targeting DHFR/DNA Gyrase Inhibitors with Immunomodulatory Activity
por: Hassan, Ashraf S., et al.
Publicado: (2020)

Biological Evaluation and Molecular Docking with In Silico Physicochemical, Pharmacokinetic and Toxicity Prediction of Pyrazolo[1,5-a]pyrimidines
por: Naglah, Ahmed M., et al.
Publicado: (2020)

Chiral Pyridine-3,5-bis- (L-phenylalaninyl-L-leucinyl) Schiff Base Peptides as Potential Anticancer Agents: Design, Synthesis, and Molecular Docking Studies Targeting Lactate Dehydrogenase-A
por: Amr, Abd El-Galil E., et al.
Publicado: (2020)

Synthesis, Docking, Computational Studies, and Antimicrobial Evaluations of New Dipeptide Derivatives Based on Nicotinoylglycylglycine Hydrazide
por: Khalaf, Hemat S., et al.
Publicado: (2020)

Synthesis, Characterization, In Vitro Anticancer Potentiality, and Antimicrobial Activities of Novel Peptide–Glycyrrhetinic-Acid-Based Derivatives
por: Moustafa, Gaber O., et al.
Publicado: (2021)

Chitosan Schiff base electrospun fabrication and molecular docking assessment for nonleaching antibacterial nanocomposite production
por: Ali, Eman AboBakr, et al.
Publicado: (2023)

Design, Synthesis and Docking Studies of Novel Macrocyclic Pentapeptides as Anticancer Multi-Targeted Kinase Inhibitors
por: Amr, Abd El-Galil E., et al.
Publicado: (2018)

Identification of Antibacterial Metabolites from Endophytic Fungus Aspergillus fumigatus, Isolated from Albizia lucidior Leaves (Fabaceae), Utilizing Metabolomic and Molecular Docking Techniques
por: Hussein, Mai E., et al.
Publicado: (2022)

Synthesis, Molecular Docking Studies, In Vitro Antimicrobial and Antifungal Activities of Novel Dipeptide Derivatives Based on N-(2-(2-Hydrazinyl-2-oxoethylamino)-2-oxoethyl)-Nicotinamide
por: Moustafa, Gaber, et al.
Publicado: (2018)

Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating
por: Sadek, Kamal Usef, et al.
Publicado: (2012)

Design, Synthesis, Anticancer Evaluation, Enzymatic Assays, and a Molecular Modeling Study of Novel Pyrazole–Indole Hybrids
por: Hassan, Ashraf S., et al.
Publicado: (2021)

Synthesis, Characterization, and Cytotoxicity of Some New 5-Aminopyrazole and Pyrazolo[1,5-a]pyrimidine Derivatives
por: Hassan, Ashraf S., et al.
Publicado: (2015)

Antibacterial and molecular docking studies of newly synthesized nucleosides and Schiff bases derived from sulfadimidines
por: Amer, Hamada H., et al.
Publicado: (2021)

Nanoparticles of a Pyrazolo-Pyridazine Derivative as Potential EGFR and CDK-2 Inhibitors: Design, Structure Determination, Anticancer Evaluation and In Silico Studies
por: Hashem, Heba E., et al.
Publicado: (2023)

Metal-Based Scaffolds of Schiff Bases Derived from Naproxen: Synthesis, Antibacterial Activities, and Molecular Docking Studies
por: Shaheen, Muhammad Ashraf, et al.
Publicado: (2019)

Cyanothioacetamides as a synthetic platform for the synthesis of aminopyrazole derivatives
por: Filimonov, Valeriy O, et al.
Publicado: (2023)

N(α)-1, 3-Benzenedicarbonyl-Bis-(Amino Acid) and Dipeptide Candidates: Synthesis, Cytotoxic, Antimicrobial and Molecular Docking Investigation
por: Naglah, Ahmed M, et al.
Publicado: (2021)

Approaches towards the synthesis of 5-aminopyrazoles
por: Aggarwal, Ranjana, et al.
Publicado: (2011)

Synthesis, Docking Studies, and In Vitro Evaluation of Some Novel Thienopyridines and Fused Thienopyridine–Quinolines as Antibacterial Agents and DNA Gyrase Inhibitors
por: Mohi El-Deen, Eman M., et al.
Publicado: (2019)

Indole Derivatives as Cyclooxygenase Inhibitors: Synthesis, Biological Evaluation and Docking Studies
por: Bhat, Mashooq Ahmad, et al.
Publicado: (2018)

Enaminonitriles in Heterocyclic Synthesis: A Route to 1,3-Diaryl-4-aminopyrazole Derivatives
por: Medrasi, Hanadi Y., et al.
Publicado: (2013)

Synthesis and Biological Evaluation of New Pyridothienopyrimidine Derivatives as Antibacterial Agents and Escherichia coli Topoisomerase II Inhibitors
por: Mohi El-Deen, Eman M., et al.
Publicado: (2020)

5-Aminopyrazole as precursor in design and synthesis of fused pyrazoloazines
por: Aggarwal, Ranjana, et al.
Publicado: (2018)

Design, synthetic approach, in silico molecular docking and antibacterial activity of quinazolin-2,4-dione hybrids bearing bioactive scaffolds
por: Abdelmonsef, Aboubakr H., et al.
Publicado: (2022)

New Inducible Nitric Oxide Synthase and Cyclooxygenase-2 Inhibitors, Nalidixic Acid Linked to Isatin Schiff Bases via Certain l-Amino Acid Bridges
por: Naglah, Ahmed M., et al.
Publicado: (2016)

Antileishmanial Aminopyrazoles: Studies into Mechanisms and Stability of Experimental Drug Resistance
por: Van den Kerkhof, M., et al.
Publicado: (2020)

Synthesis, spectroscopic and molecular docking studies on new schiff bases, nucleosides and α-aminophosphonate derivatives as antibacterial agents
por: Alotaibi, Saad H., et al.
Publicado: (2020)

Synthesis of 4-Aminopyrazol-5-ols as Edaravone Analogs and Their Antioxidant Activity
por: Burgart, Yanina V., et al.
Publicado: (2022)

Preparation, physicochemical characterization and antimicrobial activities of novel two phenolic chitosan Schiff base derivatives
por: Hassan, Mohamed A., et al.
Publicado: (2018)

Synthesis, characterization, molecular docking and biological evaluation of Schiff Base derivatives of cefpodoxime
por: Mahmood, Waqas, et al.
Publicado: (2022)

Crystal structure and Hirshfeld surface analysis of bis(3-aminopyrazole-κN (1))bis(3-aminopyrazole-κN (2))bis(nitrato-κO)copper(II)
por: Kucheriv, Olesia I., et al.
Publicado: (2023)

Exploring novel derivatives of isatin-based Schiff bases as multi-target agents: design, synthesis, in vitro biological evaluation, and in silico ADMET analysis with molecular modeling simulations
por: Hassan, Ashraf S., et al.
Publicado: (2023)

Metabolomic Profiling, Antibacterial, and Molluscicidal Properties of the Medicinal Plants Calotropis procera and Atriplex halimus: In Silico Molecular Docking Study
por: Morad, Mostafa Y., et al.
Publicado: (2023)

Novel benzoxaborole, nitroimidazole and aminopyrazoles with activity against experimental cutaneous leishmaniasis
por: Van Bocxlaer, Katrien, et al.
Publicado: (2019)

Synthesis, spectroscopic characterization, and thermal studies of novel Schiff base complexes: theoretical simulation studies on coronavirus (COVID-19) using molecular docking
por: Ahmed, Yasmin M., et al.
Publicado: (2021)

In Silico Approach Using Free Software to Optimize the Antiproliferative Activity and Predict the Potential Mechanism of Action of Pyrrolizine-Based Schiff Bases
por: Almalki, Faisal A., et al.
Publicado: (2021)

Antibacterial, Anticandidal, and Antibiofilm Potential of Fenchone: In Vitro, Molecular Docking and In Silico/ADMET Study
por: Ahmad, Wasim, et al.
Publicado: (2022)

Eco-Friendly Synthesis, Biological Evaluation, and In Silico Molecular Docking Approach of Some New Quinoline Derivatives as Potential Antioxidant and Antibacterial Agents
por: El-Saghier, Ahmed M., et al.
Publicado: (2021)

Synthesis, structural characterization, antioxidant, cytotoxic activities and docking studies of schiff base Cu(II) complexes
por: Rezk, Ghada N., et al.
Publicado: (2023)

Synthesis, electrospinning, and molecular docking of poly(methyl methacrylate) Schiff bases and their applications as polymeric antimicrobial agents and for dye removal
por: Kenawy, El-Refaie, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ial8k0eolidqp5s7nkfi3q00ih