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Identification of New Antifungal Agents Targeting Chitin Synthesis by a Chemical-Genetic Method
Fungal infection is a leading cause of mortality in immunocompromised population; thus, it is urgent to develop new and safe antifungal agents. Different from human cells, fungi have a cell wall, which is composed mainly of polysaccharide glucan and chitin. The unique cell wall structure is an ideal...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749524/ https://www.ncbi.nlm.nih.gov/pubmed/31470665 http://dx.doi.org/10.3390/molecules24173155 |