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An audit of mother to child HIV transmission rates and neonatal outcomes at a tertiary hospital in South Africa

OBJECTIVE: The aim of this study was to explore the prevalence of congenital HIV infection of neonates at Charlotte Maxeke Johannesburg Academic Hospital (CMJAH) between 2015 and 2017, as well as compare the HIV PCR positive and HIV PCR negative neonates. RESULTS: A total number of 1443 HIV exposed...

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Detalles Bibliográficos
Autores principales: Benali, Ghad, Ramdin, Tanusha, Ballot, Daynia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749619/
https://www.ncbi.nlm.nih.gov/pubmed/31533837
http://dx.doi.org/10.1186/s13104-019-4617-1
Descripción
Sumario:OBJECTIVE: The aim of this study was to explore the prevalence of congenital HIV infection of neonates at Charlotte Maxeke Johannesburg Academic Hospital (CMJAH) between 2015 and 2017, as well as compare the HIV PCR positive and HIV PCR negative neonates. RESULTS: A total number of 1443 HIV exposed neonates was examined for the study period out of a total of 5029 admissions (HIV exposure 28.6%) The study found that the rate of HIV transmission at birth was 2.52%. The majority of infants had low birth weight and were also born prematurely. These results show that, despite the introduction of the extended mother to child transmission programme, HIV transmission is high.