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Reproductive characteristics are associated with gene-specific promoter methylation status in breast cancer

BACKGROUND: Reproductive characteristics are well-established risk factors for breast cancer, but the underlying mechanisms are not fully resolved. We hypothesized that altered DNA methylation, measured in tumor tissue, could act in concert with reproductive factors to impact breast carcinogenesis....

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Detalles Bibliográficos
Autores principales: McCullough, Lauren E., Collin, Lindsay J., Conway, Kathleen, White, Alexandra J., Cho, Yoon Hee, Shantakumar, Sumitra, Terry, Mary Beth, Teitelbaum, Susan L., Neugut, Alfred I., Santella, Regina M., Chen, Jia, Gammon, Marilie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749688/
https://www.ncbi.nlm.nih.gov/pubmed/31533668
http://dx.doi.org/10.1186/s12885-019-6120-4