Abi1 loss drives prostate tumorigenesis through activation of EMT and non-canonical WNT signaling

BACKGROUND: Prostate cancer development involves various mechanisms, which are poorly understood but pointing to epithelial mesenchymal transition (EMT) as the key mechanism in progression to metastatic disease. ABI1, a member of WAVE complex and actin cytoskeleton regulator and adaptor protein, act...

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Detalles Bibliográficos
Autores principales: Nath, Disharee, Li, Xiang, Mondragon, Claudia, Post, Dawn, Chen, Ming, White, Julie R., Hryniewicz-Jankowska, Anita, Caza, Tiffany, Kuznetsov, Vladimir A., Hehnly, Heidi, Jamaspishvili, Tamara, Berman, David M., Zhang, Fan, Kung, Sonia H. Y., Fazli, Ladan, Gleave, Martin E., Bratslavsky, Gennady, Pandolfi, Pier Paolo, Kotula, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749699/
https://www.ncbi.nlm.nih.gov/pubmed/31530281
http://dx.doi.org/10.1186/s12964-019-0410-y

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