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Widespread Translational Control of Fibrosis in the Human Heart by RNA-Binding Proteins
Fibrosis is a common pathology in many cardiac disorders and is driven by the activation of resident fibroblasts. The global posttranscriptional mechanisms underlying fibroblast-to-myofibroblast conversion in the heart have not been explored. METHODS: Genome-wide changes of RNA transcription and tra...
Autores principales: | Chothani, Sonia, Schäfer, Sebastian, Adami, Eleonora, Viswanathan, Sivakumar, Widjaja, Anissa A., Langley, Sarah R., Tan, Jessie, Wang, Mao, Quaife, Nicholas M., Jian Pua, Chee, D’Agostino, Giuseppe, Guna Shekeran, Shamini, George, Benjamin L., Lim, Stella, Yiqun Cao, Elaine, van Heesch, Sebastiaan, Witte, Franziska, Felkin, Leanne E., Christodoulou, Eleni G., Dong, Jinrui, Blachut, Susanne, Patone, Giannino, Barton, Paul J.R., Hubner, Norbert, Cook, Stuart A., Rackham, Owen J.L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749977/ https://www.ncbi.nlm.nih.gov/pubmed/31284728 http://dx.doi.org/10.1161/CIRCULATIONAHA.119.039596 |
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